One Technology - Endless Opportunities

MyCell Technology – Swiss Science for better Nutraceuticals and a better World

A new technology based on the same molecular encapsulation process that our body uses to absorb fat-soluble compounds.

This process is called micellization.

Overview

Bioavailability as an essential Tool in pharmacokinetics

The uptake of an active ingredient by the intestinal tract via an oral route, i.e. the ability to enter the systemic circulation, is heavily dependent of its stability towards acids (gastric juice), enzymatic degradation (e.g. pancreatic enzymes) and water solubility. The uptake via the skin also depends on the ability of the active ingredient to bypass the upper skin layer consisting of the upper epidermis with its skin cells and fibres without blood and lymph vessels, the lower dermis and into the subcutaneous environment with its blood vessels.

In the intestinal tract, lipophilic compounds are made water-soluble by the help of the bile salts, which have amphiphilic properties. With the help of the bile salts the lipophilic components are caged in small round shaped structures, so-called micelles, which consist of an inner lipophilic and outer water-soluble moiety and thus can render lipophilic ingredients, which are a priori water insoluble, water-soluble.

However, the endogenous processes have a relatively low efficacy. They need most often stimulation of the release of the bile salts from the gall bladder by the lipophilic compound itself and stimulation by concomitant food intake. The efficacy depends on the regular motility of the intestinal tract to bring the ingredients into contact with the bile salts to form an emulsion, as well as the amount of bile salts that can be released.

Usually, this process increases the uptake of lipophilic compounds up to 5-15% bioavailability, which is sufficient for supply in healthy, young adults. In diseased or elderly persons the regular processes may, however, not be sufficient to exert the desired effect of an active ingredient or maintain health and wellness, e.g. due to hypovitaminoses of vitamin A, D, E, and K and other essential factors such as ubiquinol/ubiquinone, or essential fatty acids. Moreover, natural extracts from fruits or vegetables which often have lipophilic or resin-like, instable constituents may not be taken up anymore.

Bioavailability is
the proportion of a drug or other substance which enters the circulation when introduced into the body and so is able to have an active effect.

100 % Bioavailability

Defined by intravenous administration, the bioavailability corresponds to 100%.

5 - 15% Bioavailibility

Active ingredients administered by other routes (oral, cutaneous) reduce bioavailability due to incomplete absorption and first-pass effects.

Low Bioavailability

With age, the ability to absorb fat-soluble substances weakens.

The Power of MyCell Technology®

MyCell Technology not only leads to more effective but also more efficient active ingredients

It`s all new, and all powerful

ONE TECHNOLOGY – ENDLESS OPPORTUNITIES

An innovative technology based on the same molecular encapsulation process our body uses to absorb fat-soluble substances.

This process is called micellization.

The patented MyCell Technology mimics the creation of these micelle structures. This means the fat-soluble substances can immediately be absorbed by the body increasing the bioavailability of the active ingredient.

The encapsulated ingredients are protected against degradation by the stomach acids and faster absorption also ensures the by-passing of the liver.

Normally, fat-soluble substances have an absorption rate
of 5 to 15 %.

With the MyCell Enhanced™ technology it is possible to reach an absorption of close to 100 %.

This allows us to fully benefit from these ingredients.